The early resignation of Science Secretary Srivari Chandrasekhar is significant for several reasons:

• Chandrasekhar held an important position in the Indian government and his resignation could severely impact the functioning of the science and technology sector.
• His sudden departure has raised questions about the reasons behind his resignation and has led to speculation about government interference in the scientific community.
• Chandrasekhar was known for his efforts to promote scientific research and development in the country, and his absence could slow down progress in this area.
• The resignation also highlights the need for greater transparency in government policies and decision-making processes to ensure that qualified individuals are able to serve their positions without fear of undue political interference.
• It is also possible that there were personal reasons behind Chandrasekhar's decision to resign, but without more information, it is difficult to determine the exact cause of his departure.

Overall, the premature resignation of Science Secretary Srivari Chandrasekhar is a significant event that raises important questions about the role of science and technology in the Indian government and the need for greater transparency and accountability in decision-making processes.