According to U.S. President Joe Biden, the significance of the India-U.S. friendship is multi-faceted. Some of the key points include:

• Strategic Partnership: The India-U.S. friendship is based on a strong strategic partnership that is crucial for promoting global peace, security, and prosperity.
• Economic Ties: India and the U.S. are important trade and investment partners, and fostering this relationship can lead to job creation, economic growth, and development for both nations.

Overall, the India-U.S. friendship is seen as a vital partnership that can help strengthen ties between two of the world's largest democracies, and promote peace, security, and prosperity around the globe.